Sebaceous glands help the skin stay moist and protect it against external influences such as harsh weather, pollution, and microbial assaults: The oily or waxy matter that these microscopic, exocrine glands secrete – called sebum – lubricates and softens the skin and hair.
BASF Care Creations and the Cell Therapy Research Institute CTIBiotech presented the initial results of their joint research on 3D tissue models for the development and testing of bio-actives for skin care applications. After two years of research, the experts have now demonstrated both the ex vivo production of physiological sebum in a long-term culture of a 3D human sebaceous gland model and the regulation of this sebum production by means of active ingredients.
Using CTIBiotech’s 3D human sebaceous gland technology, scientists were able to improve BASF’s 3D skin model portfolio. The new 3D technology provides a powerful platform for skin care researchers wishing to study the function of sebaceous glands, in relation to a range of age-related, microbial and inflammatory skin disorders.
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